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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427aa28d25b4b43b74ee836dcf452efdd24a5f3a8afab2686f7c978997245ed6' 
  AND token = 'Aj1mkclRYTaNkEY2tU2AK/tieEH0C/x/3sxcRNa3J8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}