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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61652b7586a3c5e8a909c9b6db9a563444124f81de05549b8bd7cdade789d18a' 
  AND token = 'i44QTHeczMxB98HyN+2iOwQyIBUl6YKDDfPgEM7Tygs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}