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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ddd2c275b179df72242573e4a6dd81c30e0bcb421508ddfda9c972816d8e8da' 
  AND token = 'rrduZRLgyUwLrr9It1e91AwoydTTxdi7Z278xQv8ssk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}