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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddbb8141ff1986cb92f362ade1ff5923d0ed68cac45b49166bb377da456ecfcd' 
  AND token = 'P6nnDFX7A6e3Xd7FWB7hT0s8tkus5qIspm0f/YD8kNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}