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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127e20937a60281c5a7c7fee0e2c6c8c98be6e4807123decadb95e49f6fc6d90' 
  AND token = '+wZ6TbgWNAePGnUTxO4QMhGPJUG9Deat80o13sW+CnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}