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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a0d36d36a61f578b906461ddc44e71ae347c2da61cda9aabc8f655c8c47f9a' 
  AND token = 'BtjM8zlBizjwvbALfwlhu8djDfCAg6NA9CrOggJokKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}