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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00af8d7a8719e8c2d01f2209c7bf370ebe160329fa541aa62e189ab74633b1ea' 
  AND token = 'SM7Yk/vc8M5leMlPc/TjLtoIg7+z6VAjDlxJHB0Ozz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}