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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4061333a25d00f267f1a7246aad0e2508763e45e4ad7afca33897dc4a2fdbc2b' 
  AND token = 'relH94SGTMctQ/A2tegGWkGyUFssqweR5luzbWu6szU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}