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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32028fb430b0ee4e2b94e45b8c42eac2159d0a5e51d5dda6c4998752ec67b8a6' 
  AND token = 'NFCQPLrTEMEontgGGmDJv5G0yQSwkcu3nsZCq0dd1AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}