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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b98437d84d256b08340449a63a70f2685f1f66bd65607c2b5c7b873c695e43da' 
  AND token = 'MO98ikurV5GfTJ7Rdh6k2xHEEO0DYwfcGoEc4drE/ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}