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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57603b5ea4c927728c91f6df944f7e35675c6b9c4703f28f1b14b5061cb02a7c' 
  AND token = 'FvdZSF7aW/QSwZ+aSjVoNH1eE1SZOTKW3mJBiiC4DuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}