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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd325e600cae8eae24eecb2e0fa86a8c8b959e4db0af3403755381e214d6fb225' 
  AND token = 'vyDbklOF+YqIiFUm/B632jc6NYEKUYrQAqJSeo54i7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}