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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8516cd61532a6afa49b29089494c92435a08aba03033aee8bd8a41363db46354' 
  AND token = '0ekX2Rvi+kDqyqmgq0E5EZb807ElKuLUONmRs0GbSsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}