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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05289cf7c7a09da63dec4553cb8394efcbe1c057d67d6b96d4c3ab604da6db53' 
  AND token = 'mnvpxFYTy0EUsXQIXw5oky5RkmOXL7SS9CpWeXq0eL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}