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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d3c69295be6ca48eebe3900c828a1c876d011718bf03d3dcd9a23f34666a7ad' 
  AND token = '1QQo/4pqH6L4PFLUbFaOxfZbUHn+cJHGAJlPwJ6Fnn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}