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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60862159a357dc2200206c4f5c45bf721d3fa4d9e27230d8d1a288af76eeb22e' 
  AND token = 'rQWaplr4qs0pyYQ1lp13YbsgqwY2iesP/s9FOVLwUfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}