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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c492976a64b3ebe3e41afe25c895ba2193087abc729092f336a1c9311f8096' 
  AND token = 'YAIGPdcjR6xuaadC2qPFxGHIdgrOd2P2EbvnZeB1YN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}