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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b151f9f0b0608a9fa31f3dbda77b58abd5ffcb190fda9a514cf414052208f1d' 
  AND token = 'wI5Z6BxUBAifl4bSmGImeM2KSuAHT+yAbkW/pJ5cGJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}