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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af21a85b62be9cad221dc42e0067a16ba1ee1ab3b4fca2e94aa01734f655e67a' 
  AND token = '7M1wUCrT5wd7nbBEcPjEZKbWkV+zGFqm4vkkdfcZhGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}