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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7dc658a56858d4bad1f04db2bddb15189578416d8dbaa38b21367b7efdd244' 
  AND token = 'qBOs5sZ9VMOSN4QyMWhJUb3HFqbg15ixWUzoRFnq0rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}