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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41cdee6cac1be8be0f6c561e591cad84255b4a9652d2c0d8dceffdabc9a84f7' 
  AND token = 'M2gRoZ/qdl9BAF+h6htjbP7QlmqUYmaThIBde513Szk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}