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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10486cbd4ae7da4f26b82371ea9f7987f976ca73244932113cb2f304b5a623b5' 
  AND token = 'qCFKpWQdxzLWEWAUNCG0HiLnngewEv4iTAVVLMnVToQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}