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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b6293944e8f10b7dddcef34a57cabc3ba35f6a3fe16eef2c5bb61bca2d85b17' 
  AND token = 'BhBwMy4lbDqVF51c1s2paY/mdt5Ere0+AvFRWj+hqIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}