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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667f9222608d59a29c3d34f55f66307ae1958e08a8e0b38a79386b6bea2b8a14' 
  AND token = 'NJEf+I6xIM5NXOF2sTR+uwOGe5krK1j+UuLyn7eYj5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}