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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e770e0a435dc922a1bd0564b83b230bf7fbd9e94432bb68e61e9a01a4c38ec3f' 
  AND token = 'Y7n7XR7Dme8N6QC25BQY0xSxPtNKTGHBxVhEfLTPHdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}