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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd4a65d2c81ce3c28ddb73460351c2389e78582059b37c21af203ad273eeb90f' 
  AND token = 'x+gqUZ2P/AeDkLiXgZs+EnE2evAo+HMgb91zlys8ZBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}