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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9027e4960cd12e5eca2ecd8913dd17d9fb36bf5428ca8d112b7882209f334555' 
  AND token = 'pbIXEMn37BUfQ33vxGRw7NSUwgOMXUT/ngKjxIaEEgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}