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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53a32ee5b52fa3eedb94bf476478737469cd0cfa88727a914a051e6d46b2419' 
  AND token = 'pdcFNl2xG3TbJdl01iZdUHr7wWKlf6pNyQN2+8mgKG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}