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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3708c021f73e8d197e0416595bce325afc17baa17e21f08e738cf577cd6c189a' 
  AND token = 'bSKFS7Br1t1KX/K4JHB1rHwEzWY7JDKfuyxuq0WimaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}