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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf677d730f1f6d2fdffaaa98a25d3a9b56b8f85d25d5bf64a42bc7800c5f6a25' 
  AND token = 'hgnqX4U5e4Cm9NlUHqDeHovQn5nTmPxGQVBLDCj6qqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}