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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df99307ddcf19cd4eba7cd63d8df3fa46e25c8e3669ed96c93e7474c03c5f96' 
  AND token = 'mHRbTgbYLRDZVWac5Bqp5mJETTsnydC13Lz2B+rGi3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}