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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e865572c2e59c6eb07feb18765a45245624d8da57e596917e92ca10df2a5315d' 
  AND token = 'snfTifR98dMjULskl0zLVG/Nb/P+QjdpxIRxZ3YeY8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}