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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e610e1e7b37c2ab2868ec19bac03e1bcc0d7fdd70d86fac91a731e6f0417e1b' 
  AND token = 'o4ci0W9LqeBLlAyRZNd9w3BIJBl/ZystS8F1ZxZ2nhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}