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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72bea62e93ae447c5d3c8dc6a26475327660d252ff1a81e0f591f658f1136fa' 
  AND token = 'b+KCZ73rIGZS9CL9QT0taYIlbE1LxGQCd3BIxMNjUHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}