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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db164d382491cf7ebc09a8f9e6ae3756362551ae3fd5e76a076ec2a5ca10417' 
  AND token = 'UV4lgaLF2cEDXTcn3SJSJ5k2NwTWLTD8GbbOoGWYSng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}