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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b2db27ab25b25c00462cf7b2d28887376767c0b6177ee30032d597bee79b6b' 
  AND token = 'n2ZvF+nlOrVy99Vze0fXew/EUCbCxy4AdLaKBgmXp6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}