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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a7873840b49de2b079778953d8735233ef184e2d7e43a468cf75a172777478' 
  AND token = 'jM49JNNDcqSaYRr1fBr4dtw7DkYjvK++YqeVg78AeCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}