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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1438b43be11b5701e306db0b7c65db0b2d55924c44b7b8b17e1241a440273976' 
  AND token = 'mmypHQKqoY3cq4xE3tt8K5qo0BIm2opJKH8uv78h99Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}