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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8493d8bfd7241b121d7de95867b84ac0cf1a0d0c6d8e3f9ef6cc442701fb01b8' 
  AND token = '6kxD2OnvOenGI+1SwZDhiqzeceOexaAO1IHJN3u+yAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}