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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '179121af9180f9751330e24cc6a70a9765b0ad457f30236c12c99090b31f964c' 
  AND token = '7RI9obALtansBQyyRWWASfWNA27+2i+cfQbwba7RnMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}