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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fbde3fed43ea4953a6af1422618d743cada0fc66bc6462ffc995682d814b001' 
  AND token = 'aM9adsdtKgYLGEG5PVuvOokcq0fC+WoitJb+6YC5bUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}