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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37e1635f3cdf4240f690dca5da2ecbc5010d2c3d45fe7be3f2b0615c189ea8b' 
  AND token = '+5Kv7lS4Crdij2525YeFqEaJYxpX3lC0dQ2/uXlYDPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}