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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed42f6629f5cf41dbb6768126116a4db2f314d33d845c3ccb5b3d8fbc4d8b89' 
  AND token = '1HmiWG41M4NPsUFtBBDczzw1OhD8yOdZI+FBHzMgsJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}