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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5005175172f85a496dc8f82fa700e2c8e6bc95ce4483c69bc406f95a5ff8983' 
  AND token = 'AcWfe/m761MfkyxdVp9R5X3Pze81wMjsxj+bxdiUaiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}