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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e405a39958ef32b64488d356a066c9f4ec596a0af16bf8570f824d387ac309f5' 
  AND token = '1Hm0qmmSH7Cw0KSjnJw3H7UI3KDbGNs3g+BmyOs0b1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}