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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c3aad9c1cdf0964ffc39be7b8e79e6287d075dec5e824a3251f73c53f6c0ec4' 
  AND token = 'BqIWfiW+8EjLqC8rbe9+vJP6mQ6gP2ZHvAWdSH6CcsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}