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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f9fae32034deba28103303dc4a3a934f8f4c9dfa7ea06a35f8594c31af7120b' 
  AND token = 'bx4xzANeR3Yi+9YAmRZ4pCkV3srg8yLZmaeHP5DdK74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}