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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318900f8b9a4e142548b6cec02a131e3a687a3117ce66a687ceff0478edec393' 
  AND token = 'CMrQ6Pg4ycQzVllPOxugl8+dZZnvMOzb95IFf6UOG3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}