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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8391ed8eb67309f03fc7686b68ebf2c11e16c4db31e81c09d8035802e65810b0' 
  AND token = 'DIWeg1idM90D2npalGZoLg/gK7L6Uid9zk+IHuzlCYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}