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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7bf0022978e216dbbc057fb6041230ef98e18aa7c978a3dd72961650c0a245a' 
  AND token = 'dBmpR+brfm1LxjC7nVjzdO4rq/PMZ8cDOyfOFbWsPjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}